16 (S) -Iloprost

16 (S) -Iloprost is a stereoisomer of Iloprost. 16 (S) -Iloprost inhibited platelet aggregation with IC50 value of 3.5 nM, and balanced binding with platelet membrane receptors Kd value of 13.4 nM[1].

Product Specifications

CAS Number

[74843-14-4]

UNSPSC

12352211

Hazard Statement

H225-H319-H336

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/16-s-iloprost.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1C[C@@H]([C@@H]([C@H]1/C=C/[C@H]([C@H](CC#CC)C)O)C/2)CC2=C/CCCC(O)=O

Molecular Formula

C22H32O4

Molecular Weight

360.49

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Tsai AL, et al. Interaction between platelet receptor and iloprost isomers. Biochim Biophys Acta. 1988 Jul 21;942 (2) :220-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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