(R) -Morinidazole
(R) -Morinidazole is an orally active and 5-nitroimidazole antimicrobial agent that undergoes extensive metabolism in humans via N+-glucuronidation and sulfation. (R) -Morinidazole can be used for bacterial infections research including appendicitis and pelvic inflammatory disease (PID) caused by anaerobic bacteria[1].
Product Specifications
CAS Number
[898230-59-6]
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/r-morinidazole.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O[C@@H](CN1C([N+]([O-])=O)=CN=C1C)CN2CCOCC2
Molecular Formula
C11H18N4O4
Molecular Weight
270.29
Precautions
H302, H312, H332
References & Citations
[1]Zhong K, et al. Effects of renal impairment on the pharmacokinetics of morinidazole: uptake transporter-mediated renal clearanceof the conjugated metabolites. Antimicrob Agents Chemother. 2014 Jul;58 (7) :4153-61.|[2]Kong F, et al. Increased Plasma Exposures of Conjugated Metabolites of Morinidazole in Renal Failure Patients: A Critical Role of Uremic Toxins. Drug Metab Dispos. 2017 Jun;45 (6) :593-603. |[3]Lu Aifeng, et al. Application of α- (morpholine-1-yl) methyl-2-methyl-nitroimidazole-1-ethanol as anti-trichomonal agent and amebacide: China, CN1981764[P]. 2007-06-20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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