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Pomalidomide-C2-NH2

Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.

Product Specifications

Product Name Alternative

Cereblon Ligand-Linker Conjugates 15

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/e3-ligase-ligand-17.html

Purity

99.32

Solubility

10 mM in DMSO

Smiles

O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCN)=CC=C3)=O

Molecular Formula

C15H16N4O4

Molecular Weight

316.31

Precautions

H315, H319, H335

References & Citations

[1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61 (2) :543-575.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-128846/Pomalidomide-C2-NH2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-128846/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Cereblon

CAS Number

[1957235-66-3]

Available Sizes

Curated Selection

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