Pomalidomide-C2-NH2
Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.
Product Specifications
CAS Number
1957235-66-3
Product Name Alternative
Cereblon Ligand-Linker Conjugates 15
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e3-ligase-ligand-17.html
Purity
99.32
Solubility
10 mM in DMSO
Smiles
O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCN)=CC=C3)=O
Molecular Formula
C15H16N4O4
Molecular Weight
316.31
Precautions
H315, H319, H335
References & Citations
[1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61 (2) :543-575.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Frequently Asked Questions
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