Esomeprazole (sodium)
Product Specifications
UNSPSC Description
Esomeprazole sodium ((S)-Omeprazole sodium) is a potent and orally active proton pump inhibitor. Esomeprazole reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the inhibition of V-H+-ATPases[4]. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].
Target Antigen
Bacterial; Proton Pump
Type
Reference compound
Related Pathways
Anti-infection;Membrane Transporter/Ion Channel
Field of Research
Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/Esomeprazole-sodium.html
Solubility
DMSO : 100 mg/mL (ultrasonic)|Ethanol : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
O=[S@](C1=NC2=CC(OC)=CC=C2N1[Na])CC3=NC=C(C)C(OC)=C3C
Molecular Weight
367.40
References & Citations
[1]Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17(3):439-46.|[2]Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16.|[3]Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59(14):1333-9.|[4]Huarui Zhang, et al. Advances in the discovery of exosome inhibitors in cancer. J Enzyme Inhib Med Chem. 2020 Dec;35(1):1322-1330.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-17023/Esomeprazole-sodium-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17023/Esomeprazole-sodium-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
161796-78-7
Available Sizes
Curated Selection
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