N4-Methylcytidine

N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Product Specifications

CAS Number

[10578-79-7]

UNSPSC

12352005

Hazard Statement

H304, H413

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others; Cancer

Assay Protocol

https://www.medchemexpress.com/n4-methylcytidine.html

Purity

99.99

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(N=C(NC)C=C2)=O

Molecular Formula

C10H15N3O5

Molecular Weight

257.24

Precautions

H304, H413

References & Citations

[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.