Antitumor agent-189
Antitumor agent-189 (Compound DN4) is a potent antitumor agent, and a 4-oxobutanamide derivative. Antitumor agent-189 inhibits A498 cells proliferation, adhesion and invasion with an IC50 of 1.94 μM. Antitumor agent-189 also inhibits angiogenesis and tumor growth in the xenograft model of A498 cells[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352211
Target
Drug Derivative
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-189.html
Smiles
O=C(CCC(NC1=CC=C(OC)C=C1)=O)C(C2=CC(OC)=C(OC)C(OC)=C2)CC3=CC=C(OC)C=C3
Molecular Formula
C29H33NO7
Molecular Weight
507.57
References & Citations
[1]Wu C, et al. Design, synthesis and antitumor activity of novel 4-oxobutanamide derivatives. Bioorg Med Chem Lett. 2024 Nov 15;113:129978.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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