Piclamilast

[1]M J Ashton, et al. Selective type IV phosphodiesterase inhibitors as antiasthmatic agents. The syntheses and biological activities of 3- (cyclopentyloxy) -4-methoxybenzamides and analogues. J Med Chem. 1994 May 27;37 (11) :1696-703.|[2]Manuel Mata, et al. Piclamilast inhibits the pro-apoptotic and anti-proliferative responses of A549 cells exposed to H (2) O (2) via mechanisms involving AP-1 activation. Free Radic Res. 2012 May;46 (5) :690-9.|[3]Edoardo Parrella, et al. Phosphodiesterase IV inhibition by piclamilast potentiates the cytodifferentiating action of retinoids in myeloid leukemia cells. Cross-talk between the cAMP and the retinoic acid signaling pathways. J Biol Chem . 2004 Oct 1;279 (40) :42026-40.|[4]T Ukita, et al. Novel, potent, and selective phosphodiesterase-4 inhibitors as antiasthmatic agents: synthesis and biological activities of a series of 1-pyridylnaphthalene derivatives. J Med Chem. 1999 Mar 25;42 (6) :1088-99.