Propargyl-PEG1-Boc
Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[488150-84-1]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/propargyl-peg1-boc.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
O=C(OC(C)(C)C)CCOCC#C
Molecular Formula
C10H16O3
Molecular Weight
184.23
Precautions
H302, H315, H319, H335
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Alkyl/ether Linkers
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
T8666-40A-ML490 100 µL
TRRAP, CT (Transformation/Transcription Domain-associated Protein, 350/400kD PCAF-associated Factor, PAF350/400, STAF40, Tra1 Homolog, PAF400) (MaxLight 490) discontinued
Ask
View Details CO722 1 Each
Colon adenocarcinoma tissue array with matched tumor adjacent and adjacent normal tissue control, with stage and grade info, 24 cases/72 cores, replacing BC05021
Ask
View Details MBS6224644-01 0.1 mL
SIK1 (Salt-inducible Kinase 1, Serine/threonine-protein Kinase SIK1, SIK-1, SIK, Serine/threonine-protein Kinase SNF1-like Kinase 1, Serine/threonine-protein Kinase SNF1LK, SNF1LK, MSK) (MaxLight 650)
Ask
View Details 
MBS6224644-02 5x 0.1 mL
SIK1 (Salt-inducible Kinase 1, Serine/threonine-protein Kinase SIK1, SIK-1, SIK, Serine/threonine-protein Kinase SNF1-like Kinase 1, Serine/threonine-protein Kinase SNF1LK, SNF1LK, MSK) (MaxLight 650)
Ask
View Details GTR15250103 1 Vial
Lentiviral mouse Rab43 shRNA (UAS) - Lentiviral mouse Rab43 shRNA (UAS, RFP) (25)
Ask
View Details