Mouse Anti-Human CD144 Monoclonal Antibody (EX036) [PE]
vascular endothelial (VE)-cadherin (CD144) is considered to be specific markers of endothelial cells after hematopoiesis. It has been found that soluble E-cadherin (sE-cad), which is highly expressed in malignant ascites of patients with ovarian cancer, is an effective angiogenesis inducer and is released in exosome form. In mechanism, sE-cad positive exosomes heterodimerize with CD144 on endothelial cells and transmit a new sequence activation β-catenin and NFκB signaling. These data facilitate our understanding of the molecular regulation of angiogenesis in ovarian cancer.
Product Specifications
CAS Number
9007-83-4
Shipping Conditions
Gel Pack
Storage Conditions
Store at 2-8 °C. Do not freeze. Protect from light.
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