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Recombinant Human Cardiac Troponin T

Recombinant Human Cardiac Troponin T

Product Specifications

Product Name Alternative

TnT

Gene Name

TNNT2

UniProt

P45379

Reactivity

Human

Target Antigen

Troponin T, cardiac muscle

Target

Cardiac Troponin T

Type

Protein

Applications

WB

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Form

Liquid

Buffer

20 mM Tris

Function

Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

Storage Conditions

Store at 4°C if entire vial will be used within 2-4 weeks. Store at -20°C for longer periods of time. For long term storage, addition of 0.1% human serum albumin or bovine serum albumin is recommended. Avoid multiple freeze- thaw cycles.

Product Datasheet

https://www.qedbio.com/wp-content/uploads/pdf/24102P.pdf

Specificity

Cardiac Troponin T

Formulation

Sterile-filtered colorless solution in 20mM Tris, pH 8.0, 10% glycerol.

Buffer pH

pH 8.0

Target Background

Troponin T (TnT) is the tropomyosin- binding subunit of the troponin complex which is situated on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentrations. Mutations in the TNNT2 gene are associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy and hypertrophic cardiomyopathy.

CAS Number

9000-83-3

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