O-Desmethyl Galanthamine
O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid. O-Desmethyl Galanthamine is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM[1].
Product Specifications
CAS Number
[60755-80-8]
Product Name Alternative
Sanguinine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/o-desmethyl-galanthamine.html
Purity
99.70
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=C2C3=C1O[C@@]4([H])C[C@@H](O)C=C[C@@]34CCN(C)C2
Molecular Formula
C16H19NO3
Molecular Weight
273.33
Precautions
H302, H315, H319, H335
References & Citations
[1]Seydou Ka, et al. Gigantelline, gigantellinine and gigancrinine, cherylline- and crinine-type alkaloids isolated from Crinum jagus with anti-acetylcholinesterase activity. Phytochemistry. 2020 Jul;175:112390.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Curated Selection
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