JTK-101
Product Specifications
UNSPSC Description
JTK-101 is a selective HIV inhibitor. JTK-101 selectively reduces HIV-1 mRNA synthesis by inhibiting Tat cofactors, including CDK9 and cyclin T1, thereby suppressing the transcriptional activity of HIV-1. JTK-101 may be used in the field of anti-HIV virus research[1].
Target Antigen
CDK; HIV
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jtk-101.html
Smiles
N#CC1=CC=C(C=C1)CN2CCC(CC2)(OC3=C4C=C(C=CC4=CC=C35)OC)NC5=O
Molecular Weight
413.47
References & Citations
[1]Wang X, et al. Potent and selective inhibition of Tat-dependent HIV-1 replication in chronically infected cells by a novel naphthalene derivative JTK-101. Antivir Chem Chemother. 2007;18(4):201-11.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119120/JTK-101-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119120/
Clinical Information
No Development Reported
CAS Number
503048-34-8
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
