Anti-Hu CD117 PerCP-Cy™5.5
Selected Variant
T9-586-T100
Size: 100 Tests
CD117 / c-Kit (stem cell factor receptor) is a 145 kDa receptor tyrosine kinase that regulates cell proliferation, adhesion, chemotaxis, apoptosis and other cell processes. Mutations of CD117 / c-Kit can lead to growth and progression of tumours. After binding of its ligand, SCF (stem cell factor), CD117 / c-Kit is autophosphorylated on its intracellular domains and activated. CD117 is expressed on pluripotent hematopoietic progenitor cells, mast cells and various cancer cells, e.g. acute myeloid leukemia cells.
Product Specifications
Certification
RUO
Reactivity
Non-human primates, Human, Cow
Immunogen
MOLM-1 megakaryocytic cells
Target Antigen
CD117
Clone
104D2
Applications
FC (QC tested)
Format
PerCP-Cy
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody 104D2 detects extracellular part of CD117 / c-Kit protooncogen.
Applications Notes
6
Isotype
Mouse IgG1 kappa
Price
Frequently Asked Questions
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