Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Hu CD90 APC-Cy™7

CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.

Product Specifications

Certification

RUO

Negative Species

Dog

Reactivity

Pig, Horse, Human, Non-human primates

Immunogen

HEL erythroleukemia cells

Target Antigen

CD90

Clone

5E10

Applications

FC (QC tested)

Format

APC-Cy

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Chin-Yee IH, Keeney M, Stewart AK, Belch A, Bence-Buckler I, Couban S, Howson-Jan K, Rubinger M, Stewart D, Sutherland R, Paragamian V, Bhatia M, Foley R: Optimising parameters for peripheral blood leukapheresis after r-metHuG-CSF (filgrastim) and r-metHuSCF (ancestim) in patients with multiple myeloma: a temporal analysis of CD34 (+) absolute counts and subsets. Bone Marrow Transplant. 2002 Dec;30 (12) :851-60., URL: http://www.ncbi.nlm.nih.gov/pubmed/12476276 , *Hoppstädter J, Diesel B, Zarbock R, Breinig T, Monz D, Koch M, Meyerhans A, Gortner L, Lehr CM, Huwer H, Kiemer AK: Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages. Respir Res. 2010 Sep 15;11:124., URL: https://pubmed.ncbi.nlm.nih.gov/20843333/, *Carlsten M, Björkström NK, Norell H, Bryceson Y, van Hall T, Baumann BC, Hanson M, Schedvins K, Kiessling R, Ljunggren HG, Malmberg KJ: DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells. Cancer Res. 2007 Feb 1;67 (3) :1317-25., URL: http://www.ncbi.nlm.nih.gov/pubmed/17283169 , *Kroeze KL, Jurgens WJ, Doulabi BZ, van Milligen FJ, Scheper RJ, Gibbs S: Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES. J Invest Dermatol. 2009 Jun;129 (6) :1569-81., URL: http://www.ncbi.nlm.nih.gov/pubmed/19122644 , *Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34 (+) CD38 (-) hematopoietic cells. Blood. 2001 May 1;97 (9) :2741-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/11313266, *Ito T, Inaba M, Inaba K, Toki J, Sogo S, Iguchi T, Adachi Y, Yamaguchi K, Amakawa R, Valladeau J, Saeland S, Fukuhara S, Ikehara S: A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells. J Immunol. 1999 Aug 1;163 (3) :1409-19., URL: http://www.ncbi.nlm.nih.gov/pubmed/10415041 , *St Louis DC, Woodcock JB, Franzoso G, Blair PJ, Carlson LM, Murillo M, Wells MR, Williams AJ, Smoot DS, Kaushal S, Grimes JL, Harlan DM, Chute JP, June CH, Siebenlist U, Lee KP: Evidence for distinct intracellular signaling pathways in CD34+ progenitor to dendritic cell differentiation from a human cell line model. J Immunol. 1999 Mar 15;162 (6) :3237-48., URL: http://www.ncbi.nlm.nih.gov/pubmed/10092775 , *Masuda H, Anwar SS, Bühring HJ, Rao JR, Gargett CE: A novel marker of human endometrial mesenchymal stem-like cells. Cell Transplant. 2012;21 (10) :2201-14., URL: https://www.ncbi.nlm.nih.gov/pubmed/22469435, *Quardokus EM, Saunders DC, McDonough E, Hickey JW, Werlein C, Surrette C, Rajbhandari P, Martinez Casals A, Tian H, Lowery L, Neumann EK, Björklund F, Neelakantan TV, Croteau J, Wiblin AE, Fisher J, Livengood AJ, Dowell KG, Silverstein JC, Spraggins JM, Pryhuber GS, Deutsch G, Ginty F, Nolan GP, Melov S, Jonigk D, Caldwell MA, Vlachos IS, Mueller W, Gehlenborg N, Stockwell BR, Lundberg E, Snyder MP, Germain RN, Camarillo JM, Kelleher NL, Börner K, Radtke AJ: Organ mapping antibody panels: a community resource for standardized multiplexed tissue imaging. Nat Methods 2023 Aug;20 (8) :1174-1178. doi: 10.1038/s41592-023-01846-7., URL: https://pubmed.ncbi.nlm.nih.gov/37468619/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.

Applications Notes

6

Isotype

Mouse IgG1 kappa

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Camp Rabbit Polyclonal Antibody (Biotin)
orb2597033 100 µg

Camp Rabbit Polyclonal Antibody (Biotin)

Sign In for Pricing
View Details
CLK4 Rabbit Polyclonal Antibody
E28PT0973 100 µL

CLK4 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
ING4 Knockout HAP1 Polyclonal Cells
ARG27617 1 Million

ING4 Knockout HAP1 Polyclonal Cells

Sign In for Pricing
View Details
TIM3 Biosimilar Antibody
orb2669815-01 50 µg

TIM3 Biosimilar Antibody

Sign In for Pricing
View Details
TIM3 Biosimilar Antibody
orb2669815-02 100 µg

TIM3 Biosimilar Antibody

Sign In for Pricing
View Details
Anti-UPK3B Antibody (R4C01)
RHN98501 100 μg

Anti-UPK3B Antibody (R4C01)

Sign In for Pricing
View Details