Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Hu CD10 PerCP

CD10 (neutral endopeptidase – NEP, common acute lymphocytic leukemia antigen – CALLA, membrane metallo-endopeptidase – MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease, cleaving peptide bonds on the N-terminus of hydrophobic amino acids and inactivating multiple physiologically active peptids. CD10 is expressed on various normal cell types, including lymphoid precursor cells, germinal center B lymhocytes, and some epithelial cells, and its expression level serves as a marker for diagnostics of many carcinomas. CD10 is also a differentiation antigen for early B-lymphoid progenitors in the B-cell differentiation pathway and has a key role in regulation of growth, differentiation and signal transduction of many cellular systems.

Product Specifications

Certification

RUO

Immunogen

NALM-6 human pre-B cell line

Target Antigen

CD10

Clone

MEM-78

Applications

FC (QC tested)

Format

PerCP

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Horejsi V, Angelisova P, Bazil V, Kristofova H, Stoyanov S, Stefanova I, Hausner P, Vosecky M, Hilgert I: Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74) . Folia Biol (Praha) . 1988;34 (1) :23-34. , URL: https://www.ncbi.nlm.nih.gov/pubmed/2968928?dopt=A, *Leukocyte Typing IV., Knapp W. et al. (Eds.), Oxford University Press (1989) ., URL: , *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995) ., URL: , *Angelisová P, Drbal K, Horejsí V, Cerný J: Association of CD10/neutral endopeptidase 24.11 with membrane microdomains rich in glycosylphosphatidylinositol-anchored proteins and Lyn kinase. Blood. 1999 Feb 15;93 (4) :1437-9., URL: https://www.ncbi.nlm.nih.gov/pubmed/10075459?itool

Other References

*Suzuki T, Ino K, Kikkawa F, Uehara C, Kajiyama H, Shibata K, Mizutani S: Neutral endopeptidase/CD10 expression during phorbol ester-induced differentiation of choriocarcinoma cells through the protein kinase C- and extracellular signal-regulated kinase-dependent signalling pathway. Placenta. 2002 Jul;23 (6) :475-82., URL: https://pubmed.ncbi.nlm.nih.gov/12137745/, *Yada K, Kashima K, Daa T, Kitano S, Fujiwara S, Yokoyama S: Expression of CD10 in basal cell carcinoma. Am J Dermatopathol. 2004 Dec;26 (6) :463-71., URL: https://pubmed.ncbi.nlm.nih.gov/15618927/, *Braham H, Trimeche M, Ziadi S, Mestiri S, Mokni M, Amara K, Hachana M, Sriha B, Korbi S: CD10 expression by fusiform stromal cells in nasopharyngeal carcinoma correlates with tumor progression. Virchows Arch. 2006 Aug;449 (2) :220-4., URL: https://pubmed.ncbi.nlm.nih.gov/16673118/, *Dall'Era MA, True LD, Siegel AF, Porter MP, Sherertz TM, Liu AY: Differential expression of CD10 in prostate cancer and its clinical implication. BMC Urol. 2007 Mar 2;7:3., URL: https://pubmed.ncbi.nlm.nih.gov/17335564/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The antibody MEM-78 reacts with an extracellular epitope CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.

Applications Notes

6

Species

Human

CAS Number

9007-83-4

Isotype

Mouse IgG1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SDHA (NM_004168) Human Tagged ORF Clone Lentiviral Particle
RC200349L3V 200 µL

SDHA (NM_004168) Human Tagged ORF Clone Lentiviral Particle

Ask
View Details
Mir1943 Mouse qPCR Template Standard (MI0009932)
MK300141 200 Reactions

Mir1943 Mouse qPCR Template Standard (MI0009932)

Ask
View Details
TMS1 (PYCARD) Mouse Monoclonal Antibody [Clone ID: OTI1H6]
TA800099 100 µL

TMS1 (PYCARD) Mouse Monoclonal Antibody [Clone ID: OTI1H6]

Ask
View Details
PARG Polyclonal Conjugated Antibody
C27482 100 µL

PARG Polyclonal Conjugated Antibody

Ask
View Details