Anti-Hu CD177 Pacific Blue™

*Bauer S, Abdgawad M, Gunnarsson L, Segelmark M, Tapper H, Hellmark T: Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils. J Leukoc Biol. 2007 Feb;81 (2) :458-64., URL: https://www.ncbi.nlm.nih.gov/pubmed/17077162?ordin, *Sachs UJ, Andrei-Selmer CL, Maniar A, Weiss T, Paddock C, Orlova VV, Choi EY, Newman PJ, Preissner KT, Chavakis T, Santoso S: The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31) . J Biol Chem. 2007 Aug 10;282 (32) :23603-12., URL: https://www.ncbi.nlm.nih.gov/pubmed/17580308?ordin, *Mnjoyan Z, Li J, Afshar-Kharghan V: Expression of polycythemia rubra vera-1 decreases the dependency of cells on growth factors for proliferation. Haematologica. 2005 Mar;90 (3) :405-6., URL: https://www.ncbi.nlm.nih.gov/pubmed/15749675?ordin, *Stroncek DF, Caruccio L, Bettinotti M: CD177: A member of the Ly-6 gene superfamily involved with neutrophil proliferation and polycythemia vera. J Transl Med. 2004 Mar 29;2 (1) :8., URL: https://www.ncbi.nlm.nih.gov/pubmed/15050027?ordin, *Leukocyte Typing VII., Mason D. et al. (Eds.), Oxford University Press (2002) ., URL:

The antibody MEM-166 reacts with CD177 (Neutrophil specific antigen 1), a 60 kDa GPI-linked cell surface glycoprotein of uPAR family, expressed on granulocytes and in bone marrow early erythroblasts, megakaryocytes, promyelocytes and myelocytes.