Anti-Hu CD144 Alexa Fluor® 647
CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Human endothelial cells
Target Antigen
CD144
Clone
55-7H1
Applications
FC (QC tested), WB, ICC
Format
Alexa Fluor® 647
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Other References
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Isotype
Mouse IgG1 kappa
Frequently Asked Questions
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