Retagliptin (hydrochloride)
Retagliptin (SP2086) hydrochloride is a potent inhibitor of beta-amino acids and dipeptidyl peptidase-4 (DPP-4) . Retagliptin (SP2086) hydrochloride inhibits type 2 diabetes and improves glycemic control by prolonging the action of intestinal hormones such as glucagon-like peptide-1 (GLP-1) [1].
Product Specifications
CAS Number
[1174038-86-8]
Product Name Alternative
SP2086 (hydrochloride)
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/retagliptin-hydrochloride.html
Smiles
O=C(C1=C2CN(C(C[C@H](N)CC3=CC(F)=C(F)C=C3F)=O)CCN2C(C(F)(F)F)=N1)OC.Cl
Molecular Formula
C19H19ClF6N4O3
Molecular Weight
500.82
References & Citations
[1]Kim GH, et al. Enzymatic synthesis of sitagliptin intermediate using a novel ω-transaminase. Enzyme Microb Technol. 2019 Jan;120:52-60.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3
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