Anti-Hu CD305 Alexa Fluor® 488

*Colombo BM, Canevali P, Magnani O, Rossi E, Puppo F, Zocchi MR, Poggi A: Defective expression and function of the leukocyte associated Ig-like receptor 1 in B lymphocytes from systemic lupus erythematosus patients. PLoS One. 2012;7 (2) :e31903, URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=colombo+bm+canevali+p , *Poggi A, Tomasello E, Ferrero E, Zocchi MR, Moretta L: p40/LAIR-1 regulates the differentiation of peripheral blood precursors to dendritic cells induced by granulocyte-monocyte colony-stimulating factor. Eur J Immunol. 1998 Jul;28 (7) :2086-91., URL: http://www.ncbi.nlm.nih.gov/pubmed/9692876 , *Poggi A, Tomasello E, Revello V, Nanni L, Costa P, Moretta L: p40 molecule regulates NK cell activation mediated by NK receptors for HLA class I antigens and TCR-mediated triggering of T lymphocytes. Int Immunol. 1997 Sep;9 (9) :1271-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/9310830 , *Meyaard L: The inhibitory collagen receptor LAIR-1 (CD305) . J Leukoc Biol. 2008 Apr;83 (4) :799-803., URL: http://www.ncbi.nlm.nih.gov/pubmed/18063695 , *Son M, Santiago-Schwarz F, Al-Abed Y, Diamond B: C1q limits dendritic cell differentiation and activation by engaging LAIR-1. Proc Natl Acad Sci U S A. 2012 Nov 13;109 (46) :E3160-7, URL: http://www.ncbi.nlm.nih.gov/pubmed/23093673 , *Poggi A, Pella N, Morelli L, Spada F, Revello V, Sivori S, Augugliaro R, Moretta L, Moretta A: p40, a novel surface molecule involved in the regulation of the non-major histocompatibility complex-restricted cytolytic activity in humans. Eur J Immunol. 1995 Feb;25 (2) :369-76., URL: http://www.ncbi.nlm.nih.gov/pubmed/7875198 , *Warren HS: The Eighth Human Leucocyte Differentiation Antigen (HLDA8) Workshop: natural killer cell section report. Cell Immunol. 2005 Jul-Aug;236 (1-2) :17-20., URL: http://www.ncbi.nlm.nih.gov/pubmed/16157321

The mouse monoclonal antibody NKTA255 recognizes an extracellular epitope of CD305 / LAIR1, a 40 kDa type I transmembrane glycoprotein expressed on NK, T, and B cells, monocytes, dendritic cells, eosinophils, basophils, mast cells, CD34+ hematopoietic progenitor cells and thymocytes.