Anti-HLA-F PE

*Lee N, Geraghty DE: HLA-F surface expression on B cell and monocyte cell lines is partially independent from tapasin and completely independent from TAP. J Immunol. 2003 Nov 15;171 (10) :5264-71., URL: https://www.ncbi.nlm.nih.gov/pubmed/?term=hla-f+surface+expression+on+b+cell+and+monocyte+cell+lines+is+partially+independent+from+tapasin , *Lee N, Ishitani A, Geraghty DE: HLA-F is a surface marker on activated lymphocytes. Eur J Immunol. 2010 Aug;40 (8) :2308-18., URL: https://www.ncbi.nlm.nih.gov/pubmed/20865824 , *Goodridge JP, Burian A, Lee N, Geraghty DE: HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors. J Immunol. 2013 Oct 1;191 (7) :3553-62., URL: https://www.ncbi.nlm.nih.gov/pubmed/24018270 , *Burian A, Wang KL, Finton KA, Lee N, Ishitani A, Strong RK, Geraghty DE: HLA-F and MHC-I open conformers bind natural killer cell Ig-like receptor KIR3DS1. PLoS One. 2016 Sep 20;11 (9) :e0163297., URL: https://pubmed.ncbi.nlm.nih.gov/27649529/

The mouse monoclonal antibody 3D11 recognizes an extracellular epitope of HLA-F, a 42 kDa type I transbembrane protein expressed on B cells, NK cells, monocytes, and T cells, but mainly in the endoplasmic reticulum and Golgi apparatus, only a small amount on the cell surface, where, however, it can be expressed after cell activation.