Anti-N-sulfated heparan sulfate PE
Heparan sulfate (HS) proteoglycans are expressed on cell surfaces and in the extracellular matrix, and take part in developmental, regenerative, as well as pathological processes. By interaction with extracellular matrix components, growth factors, enzymes, and their inhibitors, they regulate and influence tissue distribution of the cells and biological activities of the proteins. N-sulfated heparan sulfate proteoglycans are located in specific microdomains in the plasma membrane, independent on those formed around N-acetyl-rich heparan sulfate, and play different role in the cell signaling.
Product Specifications
Certification
RUO
Immunogen
MethA murine fibrosarcoma
Target Antigen
N-sulfated heparan sulfate
Clone
HepSS-1
Applications
FC (QC tested)
Concentration
0.1 mg/mL
Format
PE
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody HepSS-1 (also known as HepSS1) recognizes N-sulfated heparan sulfate (extracellular antigen) present in many species.
Applications Notes
Flow cytometry: Recommended dilution: 2-5 μg/ml.
Species
Species independent
CAS Number
9007-83-4
Isotype
Mouse IgM
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