What is the catalog number for Anti-Hu CD87 PE?

The catalog number for Anti-Hu CD87 PE is 1P-792-T100.

What sizes are available for Anti-Hu CD87 PE?

Anti-Hu CD87 PE is available in the following size(s): 100 Tests.

Is Anti-Hu CD87 PE in stock?

Anti-Hu CD87 PE is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Hu CD87 PE?

Anti-Hu CD87 PE is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Hu CD87 PE?

Estimated delivery time for Anti-Hu CD87 PE is approximately 10 business day(s), depending on your location.

Anti-Hu CD87 PE

CD87, the urokinase plasminogen activator receptor (UPAR), is a GPI-anchored single chain glycoprotein of a 50-68 kDa, which is expressed on granulocytes, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts and keratinocytes. The urokinase plasminogen activator bound to CD87 converts plasminogen to plasmin, and being concentrated on the leading edge of migrating cells, it plays important role in cell adhesion and chemotaxis. CD87 binds to β1, β2, and β3 integrins, and can contribute to cancer cell invasion and metastasis. This antigen can also be used to study normal and abnormal granulopoiesis.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

Human myeloid cell line THP-1

Target Antigen

CD87

Clone

VIM5

Applications

FC (QC tested)

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Gleixner KV, Mayerhofer M, Sonneck K, Gruze A, Samorapoompichit P, Baumgartner C, Lee FY, Aichberger KJ, Manley PW, Fabbro D, Pickl WF, Sillaber C, Valent P: Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT. Haematologica. 2007 Nov;92 (11) :1451-9., URL: http://www.ncbi.nlm.nih.gov/pubmed/18024392 , *Lanza F, Castoldi GL, Castagnari B, Todd RF 3rd, Moretti S, Spisani S, Latorraca A, Focarile E, Roberti MG, Traniello S: Expression and functional role of urokinase-type plasminogen activator receptor in normal and acute leukaemic cells. Br J Haematol. 1998 Oct;103 (1) :110-23., URL: http://www.ncbi.nlm.nih.gov/pubmed/9792297 , *Elghetany MT, Patel J, Martinez J, Schwab H: CD87 as a marker for terminal granulocytic maturation: assessment of its expression during granulopoiesis. Cytometry B Clin Cytom. 2003 Jan;51 (1) :9-13., URL: https://www.ncbi.nlm.nih.gov/pubmed/12500292

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody VIM5 recognizes CD87 (urokinase plasminogen activator receptor), a 36-68 kDa single-chain GPI-anchored extracellular glycoprotein expressed on granulocytes, monocytes/macrophages, dendritic cells, endothelial cells, fibroblasts and keratinocytes.