What is the catalog number for Anti-Hu CD116 PE?

The catalog number for Anti-Hu CD116 PE is 1P-760-T100.

What sizes are available for Anti-Hu CD116 PE?

Anti-Hu CD116 PE is available in the following size(s): 100 Tests.

Is Anti-Hu CD116 PE in stock?

Anti-Hu CD116 PE is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Hu CD116 PE?

Anti-Hu CD116 PE is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Hu CD116 PE?

Estimated delivery time for Anti-Hu CD116 PE is approximately 10 business day(s), depending on your location.

Anti-Hu CD116 PE

CD116 (GM-CSF R alpha) is the low affinity receptor for granulocyte-macrophage colony-stimulating factor (GM-CSF) . CD116 heterodimerizes with CD131, the common beta chain subunit shared with IL-3 and IL5- receptors, to form the high affinity GM-CSF receptor. CD116 is expressed by myeloid cells including macrophages, neutrophils, eosinophils, dendritic cells, and their precursors, as well as on endothelial cells. It is being used as a specific marker of myeloid leukemias.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

CD116-transfected COS cells

Target Antigen

CD116

Clone

4H1

Applications

FC (QC tested)

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP: IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med. 2009 Jan 16;206 (1) :25-34, URL: http://www.ncbi.nlm.nih.gov/pubmed/19103877 Stomsk, *Koba C, Haruta M, Matsunaga Y, Matsumura K, Haga E, Sasaki Y, Ikeda T, Takamatsu K, Nishimura Y, Senju S: Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-β against peritoneally disseminated cancer in xenograft models. PLoS One. 2013 Jun 24;8 (6) :e67567, URL: http://www.ncbi.nlm.nih.gov/pubmed/23826321 , *Schwarzmaier D, Foell D, Weinhage T, Varga G, Däbritz J: Peripheral monocyte functions and activation in patients with quiescent Crohn's disease. PLoS One. 2013 Apr 26;8 (4) :e62761., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=schwarzmaier+d+foell+d+weinhage+t

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody 4H1 recognizes an extracellular epitope of human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.