What is the catalog number for Anti-DDIT4L PE?

The catalog number for Anti-DDIT4L PE is 1P-725-C100.

What sizes are available for Anti-DDIT4L PE?

Anti-DDIT4L PE is available in the following size(s): 0.1 mg.

Is Anti-DDIT4L PE in stock?

Anti-DDIT4L PE is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-DDIT4L PE?

Anti-DDIT4L PE is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-DDIT4L PE?

Estimated delivery time for Anti-DDIT4L PE is approximately 10 business day(s), depending on your location.

Anti-DDIT4L PE

DDIT4L (DNA-damage-inducible transcript 4-like), also known as REDD2 (regulated in development and DNA damage response 2) or RTP801L is a stress-inducted protein, which was shown to mediate monocyte cell death through a reduction in thioredoxin-1 expression, and is highly expressed in atherosclerotic lesions. Stimulation of DDIT4L expression in macrophages increases oxidized LDL-induced macrophage death.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

N-terminal recombinant fragment of human DDIT4L (amino acids 2-98)

Target Antigen

DDIT4L

Clone

DDIT-03

Applications

FC-IC (QC tested)

Concentration

0.1 mg/mL

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Other References

*Cuaz-Pérolin C, Furman C, Larigauderie G, Legedz L, Lasselin C, Copin C, Jaye M, Searfoss G, Yu KT, Duverger N, Nè gre-Salvayre A, Fruchart JC, Rouis M.REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death. Arterioscler Thromb Vasc Biol. 2004 Oct;24 (10) :1830-5., URL: https://pubmed.ncbi.nlm.nih.gov/15308555/, *Corradetti MN, Inoki K, Guan KL: The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway. J Biol Chem. 2005 Mar 18;280 (11) :9769-72. , URL: http://www.ncbi.nlm.nih.gov/pubmed/15632201, , *Imen JS, Billiet L, Cuaz-Pérolin C, Michaud N, Rouis M: The regulated in development and DNA damage response 2 (REDD2) gene mediates human monocyte cell death through a reduction in thioredoxin-1 expression. Free Radic Biol Med. 2009 May 15;46 (10) :1404-10, URL: https://pubmed.ncbi.nlm.nih.gov/19268525/

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody DDIT-03 recognizes DDIT4L / REDD2 protein, which belongs to intracellular stress-induced proteins involved in mediation of cell death.