Anti-TNF alpha PE
TNF-alpha is a cytokine produced by monocytes, macrophages, neutrophils, NK cells, CD4+ T cells and many transformed cells. It can be expressed as a 17 kDa free molecule, or as a 26 kDa membrane protein. TNF-alpha easily forms stable trimers, but also other multimeric complexes. In the immune system, it is an important regulator, which has cytolytic and cytostatic activity against a range of tumor cells, increases fibroblast proliferation and supports neutrophil chemotaxis and phagocytosis.
Product Specifications
Certification
RUO
Immunogen
Recombinant human TNF-alpha
Target Antigen
TNF alpha
Clone
MAb11
Applications
FC-IC (QC tested)
Format
PE
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The mouse monoclonal antibody MAb11 recognizes human 17-26 kDa cytokine TNF-alpha (tumor necrosis factor alpha) .
Applications Notes
6
Species
Pig, Human, Non-human primates
CAS Number
9007-83-4
Isotype
Mouse IgG1 kappa
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items