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Anti-Cyclin D1 PE

Product Specifications

Clone

DCS-6

Format

PE

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Bosone I, Cavalla P, Chiadò -Piat L, Vito ND, Schiffer D: Cyclin D1 expression in normal oligodendroglia and microglia cells: its use in the differential diagnosis of oligodendrogliomas. Neuropathology. 2001 Sep;21 (3) :155-61. , URL: http://www.ncbi.nlm.nih.gov/pubmed/11666011 , *Jain P, Giustolisi GM, Atkinson S, Elnenaei MO, Morilla R, Owusu-Ankomah K, Rafiq-Mohammed F, Matutes E, Wotherspoon A, Catovsky D: Detection of cyclin D1 in B cell lymphoproliferative disorders by flow cytometry. J Clin Pathol. 2002 Dec;55 (12) :940-5., URL: http://www.ncbi.nlm.nih.gov/pubmed/12461064 , *Albrecht JH, Hansen LK: Cyclin D1 promotes mitogen-independent cell cycle progression in hepatocytes. Cell Growth Differ. 1999 Jun;10 (6) :397-404., URL: http://www.ncbi.nlm.nih.gov/pubmed/10392901 , *Zwijsen RM, Buckle RS, Hijmans EM, Loomans CJ, Bernards R: Ligand-independent recruitment of steroid receptor coactivators to estrogen receptor by cyclin D1. Genes Dev. 1998 Nov 15;12 (22) :3488-98., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=Zwijsen+rm+buckle+rs+bernards+r , *Fredersdorf S, Burns J, Milne AM, Packham G, Fallis L, Gillett CE, Royds JA, Peston D, Hall PA, Hanby AM, Barnes DM, Shousha S, O'Hare MJ, Lu X: High level expression of p27 (kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27 (kip1) and degree of malignancy in human breast and colorectal cancers. Proc Natl Acad Sci U S A. 1997 Jun 10;94 (12) :6380-5., URL: https://pubmed.ncbi.nlm.nih.gov/9177226/

Other References

*Diehl JA, Zindy F, Sherr CJ: Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway. Genes Dev. 1997 Apr 15;11 (8) :957-72., URL: https://www.ncbi.nlm.nih.gov/pubmed/9136925?ordina, *Diehl JA, Cheng M, Roussel MF, Sherr CJ: Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 1998 Nov 15;12 (22) :3499-511., URL: https://www.ncbi.nlm.nih.gov/pubmed/9832503?ordina, *Yang W, Zhang Y, Li Y, Wu Z, Zhu D: Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1. J Biol Chem. 2007 Feb 9;282 (6) :3799-808., URL: https://www.ncbi.nlm.nih.gov/pubmed/17130121?ordin, *Mukherji A, Janbandhu VC, Kumar V: GSK-3beta-dependent destabilization of cyclin D1 mediates replicational stress-induced arrest of cell cycle. FEBS Lett. 2008 Mar 6, URL: https://www.ncbi.nlm.nih.gov/pubmed/18328826?ordin

CAS Number

9007-83-4

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