What is the catalog number for Anti-Hu CD1b FITC?

The catalog number for Anti-Hu CD1b FITC is 1F-761-T100.

What sizes are available for Anti-Hu CD1b FITC?

Anti-Hu CD1b FITC is available in the following size(s): 100 Tests.

Is Anti-Hu CD1b FITC in stock?

Anti-Hu CD1b FITC is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Hu CD1b FITC?

Anti-Hu CD1b FITC is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Hu CD1b FITC?

Estimated delivery time for Anti-Hu CD1b FITC is approximately 10 business day(s), depending on your location.

Anti-Hu CD1b FITC

CD1b (also known as R1) together with CD1a and c, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. Besides non-peptide glycolipid antigen presentation to CD1-restricted T cells, CD1b has been implicated in thymocyte development.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

A cell membrane antigen preparation that was isolated from normal human thymocytes

Target Antigen

CD1b

Clone

SN13

Applications

FC (QC tested)

Format

FITC

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Hayes SM, Knight KL: Group 1 CD1 genes in rabbit. J Immunol. 2001 Jan 1;166 (1) :403-10., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=hayes+sm+knight+kl , *Tentori L, Graziani G, Porcelli SA, Sugita M, Brenner MB, Madaio R, Bonmassar E, Giuliani A, Aquino A: Rifampin increases cytokine-induced expression of the CD1b molecule in human peripheral blood monocytes. Antimicrob Agents Chemother. 1998 Mar;42 (3) :550-4., URL: http://www.ncbi.nlm.nih.gov/pubmed/9517931 , *Giuliani A, Prete SP, Graziani G, Aquino A, Balduzzi A, Sugita M, Brenner MB, Iona E, Fattorini L, Orefici G, Porcelli SA, Bonmassar E: Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells. Infect Immun. 2001 Dec;69 (12) :7461-70., URL: http://www.ncbi.nlm.nih.gov/pubmed/11705921, *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997) ., URL:

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The mouse monoclonal antibody SN13 (also known as K5-1B8) recognizes an extracellular epitope of CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells.