Anti-Ms CD106 FITC
CD106 / VCAM-1 (vascular cell adhesion molecule-1) is an Ig-like cell surface adhesion molecule binding VLA-4 integrin. VCAM-1 is a potent T cell costimulatory molecule taking part in their positive selection and survival, as well as in adhesion, transendothelial migration and activation of peripheral T cells. VCAM-1 is also involved in endothelial cell-cell contacts. Whereas VCAM-1 normally mediates leukocyte extravasion to sites of tissue inflammation, tumour cells can use overexpressed VCAM-1 to escape T cell immunity.
Product Specifications
Certification
RUO
Immunogen
Murine preadipose cell line PA6
Target Antigen
CD106
Clone
429 (MVCAM.A)
Applications
FC (QC tested)
Concentration
0.5 mg/mL
Format
FITC
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Species
Mouse
CAS Number
9007-83-4
Isotype
Rat IgG2a kappa
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