What is the catalog number for Anti-Hu CD108 FITC?

The catalog number for Anti-Hu CD108 FITC is 1F-275-T100.

What sizes are available for Anti-Hu CD108 FITC?

Anti-Hu CD108 FITC is available in the following size(s): 100 Tests.

Is Anti-Hu CD108 FITC in stock?

Anti-Hu CD108 FITC is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Hu CD108 FITC?

Anti-Hu CD108 FITC is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Hu CD108 FITC?

Estimated delivery time for Anti-Hu CD108 FITC is approximately 10 business day(s), depending on your location.

Anti-Hu CD108 FITC

CD108 (Sema7A) is a GPI-anchored semaphorin family member, which enhances central and peripheral axonal growth and is required for proper axon track formation during ebryogenesis. CD108 also regulates osteoclast differentiation and pre-osteoblastic cell migration, and in immune system affects cell proliferation, chemotaxis and cytokine release. On erythrocytes CD108 defines the JMH (John-Milton-Hagen) human blood group. CD108 signalizes through its receptors – plexin C1 and beta1 integrins.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

HPB-ALL human T cell line

Target Antigen

CD108

Clone

MEM-150

Applications

FC (QC tested)

Format

FITC

Buffer

Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

References & Citations

*Angelisova P, Drbal K, Cerny J, Hilgert I, Horejsi V: Characterization of the human leukocyte GPI-anchored glycoprotein CDw108 and its relation to other similar molecules. Immunobiology. 1999 Jun;200 (2) :234-45., URL: https://www.ncbi.nlm.nih.gov/pubmed/10416131?dopt=, *Leukocyte Typing VI., Kishimoto T. et al. (Eds.), Garland Publishing Inc. (1997) ., URL: , *Leukocyte Typing V., Schlossman S. et al. (Eds.), Oxford University Press (1995) ., URL: , *Mudad R, Rao N, Angelisova P, Horejsi V, Telen MJ.: Evidence that CDw108 membrane protein bears the JMH blood group antigen. Transfusion. 1995 Jul;35 (7) :566-70. , URL: https://www.ncbi.nlm.nih.gov/pubmed/7631388?dopt=A

Other References

*Pasterkamp RJ, Peschon JJ, Spriggs MK, Kolodkin AL: Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature. 2003 Jul 24;424 (6947) :398-405., URL: https://www.ncbi.nlm.nih.gov/pubmed/12879062?ordin, *Delorme G, Saltel F, Bonnelye E, Jurdic P, Machuca-Gayet I: Expression and function of semaphorin 7A in bone cells. Biol Cell. 2005 Jul;97 (7) :589-97., URL: https://www.ncbi.nlm.nih.gov/pubmed/15859945?ordin, *Pasterkamp RJ, Kolk SM, Hellemons AJ, Kolodkin AL: Expression patterns of semaphorin7A and plexinC1 during rat neural development suggest roles in axon guidance and neuronal migration. BMC Dev Biol. 2007 Aug 29;7:98., URL: https://www.ncbi.nlm.nih.gov/pubmed/17727705?ordin, *Suzuki K, Okuno T, Yamamoto M, Pasterkamp RJ, Takegahara N, Takamatsu H, Kitao T, Takagi J, Rennert PD, Kolodkin AL, Kumanogoh A, Kikutani H: Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. Nature. 2007 Apr 5;446 (7136) :680-4., URL: https://www.ncbi.nlm.nih.gov/pubmed/17377534?ordin

Storage Conditions

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Specificity

The antibody MEM-150 reacts with CD108 (JMH blood group antigen), a 80 kDa GPI-anchored extracellular glycoprotein expressed on various cell types including erythrocytes, lymphoblasts; at low levels it is present on circulating lymphocytes.