Anti-betaIII-Tubulin FITC
The betaIII isoform of tubulin is present dominantly in cells of neuronal origin and it is one of the earliest markers of neuronal differentiation. It is regarded as a specific probe for the cells of neuronal origin as well as for the tumours originating from these cells. The betaIII-tubulin is most abundant in cells of neuronal origin, but was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues.
Product Specifications
Certification
RUO
Reactivity
Dog, Mouse, Rat, Pig, Human
Immunogen
Peptide (C) 441-448 coupled to maleimide-activated keyhole limpet hemocyanin via cysteine added to the N-terminus of the neuron-specific peptide.
Target Antigen
BetaIII-Tubulin
Clone
TU-20
Applications
FC (QC tested), ICC
Concentration
1 mg/mL
Format
FITC
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
The antibody TU-20 recognizes C-terminal peptide sequence ESESQGPK (aa 441-448) of neuron-specific human betaIII-tubulin.
Applications Notes
Flow cytometry: Recommended dilution: 1-3 μg/ml. Intracellular staining.
Isotype
Mouse IgG1
Frequently Asked Questions
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