Liensinine (Diperchlorate)
Liensinine Diperchlorate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlorate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlorate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].
Product Specifications
CAS Number
[5088-90-4]
UNSPSC
12352005
Target
Autophagy; Mitophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/liensinine-diperchlor-ate.html
Purity
99.96
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=Cl(=O)(O)=O.CN1[C@@H](C2=CC(OC3=CC(C[C@@H]4C5=CC(OC)=C(OC)C=C5CCN4C)=CC=C3O)=C(OC)C=C2CC1)CC6=CC=C(O)C=C6.O=Cl(=O)(O)=O
Molecular Formula
C37H44Cl2N2O14
Molecular Weight
811.66
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
Phase 2
Available Sizes
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