Anti-Hu CD274 FITC
CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor (s) for CD274 is likely.
Product Specifications
Certification
RUO
Immunogen
Full length human CD274
Target Antigen
CD274
Clone
29E.2A3
Applications
FC (QC tested)
Format
FITC
Buffer
Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Species
Non-human primates, Human
CAS Number
9007-83-4
Isotype
Mouse IgG2b kappa
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