Anti-Hu CD271 Biotin
CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.
Product Specifications
Certification
RUO
Negative Species
Mouse,Rat
Immunogen
Purified CD271 protein isolated from human melanoma cell line A875
Target Antigen
CD271
Clone
NGFR5
Applications
FC (QC tested), IP, WB, IHC-P, ICC, FC-IC (verified)
Concentration
1 mg/mL
Format
Biotin
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Extracellular and intracellular staining; recommended dilution: 1-4 µg/ml.
Species
Human, Rabbit, Cat, Non-human primates, Ferret
CAS Number
9007-83-4
Isotype
Mouse IgG1
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