Anti-Hu Ig Lambda Light Chain APC

Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa) . Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30.

Product Specifications

Certification

RUO

Negative Species

Rabbit,Hamster,Sheep,Guinea pig,Goat

Reactivity

Human

Target Antigen

Ig Lambda Light Chain

Clone

4C2

Applications

FC (QC tested)

Format

APC

Buffer

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjø nnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4 (3) :566-77., URL: https://www.ncbi.nlm.nih.gov/pubmed/23933259

Other References

*Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh) . 1975;194:77-95., URL: https://www.ncbi.nlm.nih.gov/pubmed/47690?ordinalp