Anti-Hu CD58 APC
CD58 (LFA-3) is an immunoglobulin family adhession molecule expressed by both hematopoietic and non-hematopoietic cells (often on antigen presenting cells) and serving as ligand of CD2. This interaction is important for T cell-mediated immunity. CD58 is expressed in transmembrane form and in GPI-anchored form; the later is constitutively associated with protein kinases whereas the transmembrane form activates kinase activity upon triggering. CD58 is a powerful tool for detection of minimal residual disease in acute lymphocytic leukemia, and for evaluation of liver damage related with hepatitis B.
Product Specifications
Certification
RUO
Immunogen
NALM-6 human pre-B cell line
Target Antigen
CD58
Clone
MEM-63
Applications
FC (QC tested)
Format
APC
Buffer
Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
Other References
Storage Conditions
Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
Specificity
Applications Notes
6
Species
Pig, Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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