Anti-Hu CD266 Purified Low Endotoxin
CD266 / TWEAK R (TNFRSF12A), also known as FN14 (fibroblast growth factor-inducible 14) is a receptor for CD255 / TWEAK, the TNF-like weak inducer of apoptosis. CD266 is expressed on endothelial cells, as well as on some cancer tissues, and plays a role in CD255-induced endothelial cell migration, proliferation, and angiogenesis. The CD255-CD266 interaction, or antibody-mediated triggering of CD266 is also able to induce apoptosis and necrosis in CD266-positive cells (including tumor cells), which might have therapeutic potential.
Product Specifications
Certification
RUO
Immunogen
Human CD266-transfected P815 cells
Target Antigen
CD266
Clone
ITEM-4
Applications
FC (QC tested), WB, IHC-F, FUNC
Concentration
1 mg/mL
Format
Purified Low Endotoxin
Buffer
Phosphate buffered saline (PBS), pH 7.4
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Species
Mouse, Human
CAS Number
9007-83-4
Isotype
Mouse IgG2b
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