Anti-Hu CD229 Purified Low Endotoxin

*Romero X, Zapater N, Calvo M, Kalko SG, de la Fuente MA, Tovar V, Ockeloen C, Pizcueta P, Engel P: CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse. J Immunol. 2005 Jun 1;174 (11) :7033-42., URL: https://www.ncbi.nlm.nih.gov/pubmed/15905546?itool, *de la Fuente MA, Tovar V, Villamor N, Zapater N, Pizcueta P, Campo E, Bosch J, Engel P: Molecular characterization and expression of a novel human leukocyte cell-surface marker homologous to mouse Ly-9. Blood. 2001 Jun 1;97 (11) :3513-20., URL: https://www.ncbi.nlm.nih.gov/pubmed/11369645?itool, *Martín M, Del Valle JM, Saborit I, Engel P: Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229. J Immunol. 2005 May 15;174 (10) :5977-86., URL: https://www.ncbi.nlm.nih.gov/pubmed/15879090?itool

*Sintes J, Romero X, Marin P, Terhorst C, Engel P: Differential expression of CD150 (SLAM) family receptors by human hematopoietic stem and progenitor cells. Exp Hematol. 2008 Sep;36 (9) :1199-204., URL: https://www.ncbi.nlm.nih.gov/pubmed/18495325?itool, *Romero X, Benítez D, March S, Vilella R, Miralpeix M, Engel P: Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4) . Tissue Antigens. 2004 Aug;64 (2) :132-44., URL: https://www.ncbi.nlm.nih.gov/pubmed/15245368?itool, *Bund D, Mayr C, Kofler DM, Hallek M, Wendtner CM: Human Ly9 (CD229) as novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (B-CLL) recognized by autologous CD8+ T cells. Exp Hematol. 2006 Jul;34 (7) :860-9., URL: https://www.ncbi.nlm.nih.gov/pubmed/16797413?itool, *Del Valle JM, Engel P, Martín M: The cell surface expression of SAP-binding receptor CD229 is regulated via its interaction with clathrin-associated adaptor complex 2 (AP-2) . J Biol Chem. 2003 May 9;278 (19) :17430-7., URL: https://www.ncbi.nlm.nih.gov/pubmed/12621057?itool

The mouse monoclonal antibody HLy9.25 (also known as HLy9.1.25) recognizes an extracellular epitope of CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.