Anti-Hu CD274 Purified Low Endotoxin
CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its receptor CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor (s) for CD274 is likely.
Product Specifications
Certification
RUO
Reactivity
Non-human primates, Human
Immunogen
Full length human CD274
Target Antigen
CD274
Clone
29E.2A3
Applications
IHC-F, FC (QC tested), FUNC
Concentration
1 mg/mL
Format
Purified Low Endotoxin
Buffer
Phosphate buffered saline (PBS), pH 7.4
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Functional application: Blocking. Immunohistochemistry (frozen sections) : Acetone fixation. Flow cytometry: Recommended dilution: 1-4 µg/ml
Isotype
Mouse IgG2b kappa
Frequently Asked Questions
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