Anti-Hu CD42b Purified Low Endotoxin
CD42b (GPIb alpha) composes together with GPIb beta, GPIX and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular weight kininogen, TSP-1, integrin Mac-1 and P-selectin. The extracellular domain of CD42b by its interactions also contributes to metastasis.
Product Specifications
Certification
RUO
Immunogen
Human platelets
Target Antigen
CD42b
Clone
AK2
Applications
FC (QC tested), IP, WB, ICC, ELISA
Concentration
1 mg/mL
Format
Purified Low Endotoxin
Buffer
Phosphate buffered saline (PBS), pH 7.4
References & Citations
Other References
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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