What is the catalog number for Anti-Hu CD65 Purified?

The catalog number for Anti-Hu CD65 Purified is 11-793-C100.

What sizes are available for Anti-Hu CD65 Purified?

Anti-Hu CD65 Purified is available in the following size(s): 0.1 mg.

Is Anti-Hu CD65 Purified in stock?

Anti-Hu CD65 Purified is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Hu CD65 Purified?

Anti-Hu CD65 Purified is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Hu CD65 Purified?

Estimated delivery time for Anti-Hu CD65 Purified is approximately 10 business day(s), depending on your location.

Anti-Hu CD65 Purified

CD65 is a fucosylated carbohydrate antigen (ceramide-dodecasaccharide, type II fucoganglioside), which serves as a ligand for CD62E (E-selectin) . Its structure is Gal beta1-4 GlcNAc beta1-3 Gal beta1-4 GlcNAc (3-1 Fuc alpha) beta1-3 ceramide. Unlike CD65s, the CD65 antigen does not contain terminal sialic acid, the rest of their structure is identical. CD65 is expressed on granulocytes and monocytes and participates in cell adhesion. It has been reported as important for extravascular infiltration of acute monocytic leukemia cells.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

THP-1 cell line

Target Antigen

CD65

Clone

VIM8

Applications

FC (QC tested)

Concentration

1 mg/mL

Format

Purified

Buffer

Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

References & Citations

*Kniep B, Peter-Katalinic J, Müthing J, Majdic O, Pickl WF, Knapp W: The CDw65 monoclonal antibodies VIM-8 and VIM-11 bind to the neutral glycolipid V3FucnLc8Cer. J Biochem. 1996 Mar;119 (3) :456-62., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=kniep+b+peter-katalinic+j+muthing+j+majdic+o , *Paietta E, Neuberg D, Bennett JM, Dewald G, Rowe JM, Cassileth PA, Cripe L, Tallman MS, Wiernik PH and the Eastern Cooperative Oncology Group: Low expression of the myeloid differentiation antigen CD65s, a feature of poorly differentiated AML in older adults: study of 711 patients enrolled in ECOG trials. Leukemia. 2003 Aug;17 (8) :1544-50., URL: http://www.ncbi.nlm.nih.gov/pubmed/12886241

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The mouse monoclonal antibody VIM8 recognizes human CD65, an asialo-fucoganglioside expressed on the surface of peripheral blood granulocytes (highly) and monocytes (weakly) .