What is the catalog number for Anti-Ms CD41 Purified?

The catalog number for Anti-Ms CD41 Purified is 11-763-C100.

What sizes are available for Anti-Ms CD41 Purified?

Anti-Ms CD41 Purified is available in the following size(s): 0.1 mg.

Is Anti-Ms CD41 Purified in stock?

Anti-Ms CD41 Purified is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-Ms CD41 Purified?

Anti-Ms CD41 Purified is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-Ms CD41 Purified?

Estimated delivery time for Anti-Ms CD41 Purified is approximately 10 business day(s), depending on your location.

Anti-Ms CD41 Purified

CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.

Product Specifications

Certification

RUO

Reactivity

Mouse

Immunogen

Murine platelets

Target Antigen

CD41

Clone

MWReg30

Applications

FC (QC tested), IP, IHC-P, IHC-F, ELISA

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

References & Citations

*Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX: Stress-induced hematopoietic failure in the absence of immediate early response gene X-1. Haematologica. 2013 Sep 20. [Epub ahead of print], URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=ramsey+h+steensma+dp , *Sullivan BP, Wang R, Tawfik O, Luyendyk JP: Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies. Toxicol Sci. 2010 May;115 (1) :286-94., URL: http://www.ncbi.nlm.nih.gov/pubmed/20133375 , *Boisset JC, Clapes T, Van Der Linden R, Dzierzak E, Robin C: Integrin α IIb (CD41) plays a role in the maintenance of hematopoietic stem cell activity in the mouse embryonic aorta. Biol Open. 2013 Apr 11;2 (5) :525-32., URL: http://www.ncbi.nlm.nih.gov/pubmed/23789102 , *Brancaleone V, Gobbetti T, Cenac N, le Faouder P, Colom B, Flower RJ, Vergnolle N, Nourshargh S, Perretti M: A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation. Blood. 2013 Jul 25;122 (4) :608-17., URL: https://pubmed.ncbi.nlm.nih.gov/23733341/

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

The rat monoclonal antibody MWReg30 recognizes an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 kDa) and GPIIb beta (light chain; 23 kDa) . CD41 is mainly expressed on platelets and megakaryocytes.