Anti-Hu CD116 Purified

*Huntington ND, Legrand N, Alves NL, Jaron B, Weijer K, Plet A, Corcuff E, Mortier E, Jacques Y, Spits H, Di Santo JP: IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med. 2009 Jan 16;206 (1) :25-34, URL: http://www.ncbi.nlm.nih.gov/pubmed/19103877 Stomsk, *Koba C, Haruta M, Matsunaga Y, Matsumura K, Haga E, Sasaki Y, Ikeda T, Takamatsu K, Nishimura Y, Senju S: Therapeutic effect of human iPS-cell-derived myeloid cells expressing IFN-β against peritoneally disseminated cancer in xenograft models. PLoS One. 2013 Jun 24;8 (6) :e67567, URL: http://www.ncbi.nlm.nih.gov/pubmed/23826321 , *Schwarzmaier D, Foell D, Weinhage T, Varga G, Däbritz J: Peripheral monocyte functions and activation in patients with quiescent Crohn's disease. PLoS One. 2013 Apr 26;8 (4) :e62761., URL: http://www.ncbi.nlm.nih.gov/pubmed/?term=schwarzmaier+d+foell+d+weinhage+t

The mouse monoclonal antibody 4H1 recognizes an extracellular epitope of human CD116, the GM-CSF receptor alpha subunit (approx. 80 kDa) expressed e.g. by neutrophils, eosinophils, monocytes and macrophages.