Anti-Hu CD160 Purified
CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.
Product Specifications
Certification
RUO
Immunogen
Human NK cell line YT2C2
Target Antigen
CD160
Clone
BY55
Applications
FC (QC tested), IP
Concentration
1 mg/mL
Format
Purified
Buffer
Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-4 μg/ml.
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgM kappa
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