Anti-Hu GARP Purified
GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.
Product Specifications
Certification
RUO
Reactivity
Human
Immunogen
Purified human sGARP protein
Target Antigen
GARP
Clone
GARP5
Applications
WB, FC
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Western blotting: Recommended dilution: 1-2 μg/ml; positive control: human thrombocytes, reducing conditions
Isotype
Mouse IgG1
Frequently Asked Questions
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