Anti-Ms CD45R Purified
CD45R, also known as B220, is a receptor-type protein tyrosine phosphatase glycoprotein. It is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45R expression also identifies a subset of murine bone marrow cells able to form osteoclast-like cells.
Product Specifications
Certification
RUO
Reactivity
Cat, Mouse, Human
Immunogen
Abelson murine leukemia virus-induced pre-B tumor cells
Target Antigen
CD45R
Clone
RA3-6B2
Applications
FC (QC tested), IP, IHC-P, IHC-F, ICC
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 1-4 µg/ml
Isotype
Rat IgG2a kappa
Frequently Asked Questions
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