What is the catalog number for Anti-TFG Purified?

The catalog number for Anti-TFG Purified is 11-709-C100.

What sizes are available for Anti-TFG Purified?

Anti-TFG Purified is available in the following size(s): 0.1 mg.

Is Anti-TFG Purified in stock?

Anti-TFG Purified is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Anti-TFG Purified?

Anti-TFG Purified is manufactured by AFG-XBO.

What is the estimated delivery time for Anti-TFG Purified?

Estimated delivery time for Anti-TFG Purified is approximately 10 business day(s), depending on your location.

Anti-TFG Purified

TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO) . TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.

Product Specifications

Certification

RUO

Reactivity

Human

Immunogen

Human recombinant protein Trx-his-NTFG

Target Antigen

TFG

Clone

TFG-03

Applications

IP, WB, ICC

Concentration

1 mg/mL

Format

Purified

Buffer

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Other References

*Miranda C, Roccato E, Raho G, Pagliardini S, Pierotti MA, Greco A: The TFG protein, involved in oncogenic rearrangements, interacts with TANK and NEMO, two proteins involved in the NF-kappaB pathway. J Cell Physiol. 2006 Jul;208 (1) :154-60., URL: http://www.ncbi.nlm.nih.gov/pubmed/16547966, , *Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y, Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H, Sugano S: Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene. 2003 May 22;22 (21) :3307-18., URL: https://pubmed.ncbi.nlm.nih.gov/12761501/