*Lode HN, Xiang R, Pertl U, Förster E, Schoenberger SP, Gillies SD, Reisfeld RA: Melanoma immunotherapy by targeted IL-2 depends on CD4 (+) T-cell help mediated by CD40/CD40L interaction. J Clin Invest. 2000 Jun;105 (11) :1623-30., URL: https://www.ncbi.nlm.nih.gov/pubmed/10841521?itool, *Fischbein MP, Ardehali A, Yun J, Schoenberger S, Laks H, Irie Y, Dempsey P, Cheng G, Fishbein MC, Bonavida B: CD40 signaling replaces CD4+ lymphocytes and its blocking prevents chronic rejection of heart transplants. J Immunol. 2000 Dec 15;165 (12) :7316-22., URL: https://www.ncbi.nlm.nih.gov/pubmed/11120867?itool, *Hwang Y, Nahm MH, Briles DE, Thomas D, Purkerson JM: Acquired, but not innate, immune responses to Streptococcus pneumoniae are compromised by neutralization of CD40L. Infect Immun. 2000 Feb;68 (2) :511-7., URL: https://www.ncbi.nlm.nih.gov/pubmed/10639411?itool, *Murakawa T, Kerklo MM, Zamora MR, Wei Y, Gill RG, Henson PM, Grover FL, Nicolls MR: Simultaneous LFA-1 and CD40 ligand antagonism prevents airway remodeling in orthotopic airway transplantation: implications for the role of respiratory epithelium as a modulator of fibrosis. J Immunol. 2005 Apr 1;174 (7) :3869-79., URL: https://www.ncbi.nlm.nih.gov/pubmed/15778341?itool, *Salgado CG, Nakamura K, Sugaya M, Tada Y, Asahina A, Koyama Y, Irie S, Tamaki K: Functional CD40 ligand is expressed on epidermal Langerhans cells. J Leukoc Biol. 1999 Aug;66 (2) :281-5., URL: https://www.ncbi.nlm.nih.gov/pubmed/10449168?itool, *Wu Y, Zhou Q, Zheng P, Liu Y: CD28-independent induction of T helper cells and immunoglobulin class switches requires costimulation by the heat-stable antigen. J Exp Med. 1998 Apr 6;187 (7) :1151-6., URL: https://www.ncbi.nlm.nih.gov/pubmed/9529332?itool=, *Luzina IG, Atamas SP, Storrer CE, daSilva LC, Kelsoe G, Papadimitriou JC, Handwerger BS: Spontaneous formation of germinal centers in autoimmune mice. J Leukoc Biol. 2001 Oct;70 (4) :578-84., URL: https://www.ncbi.nlm.nih.gov/pubmed/11590194?itool, *Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, Housseau F: Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. J Exp Med. 2003 Jul 7;198 (1) :31-8., URL: https://www.ncbi.nlm.nih.gov/pubmed/12847135?itool, *Howard LM, Miga AJ, Vanderlugt CL, Dal Canto MC, Laman JD, Noelle RJ, Miller SD: Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis. J Clin Invest. 1999 Jan;103 (2) :281-90., URL: https://www.ncbi.nlm.nih.gov/pubmed/9916140?itool=, *Noelle RJ, Roy M, Shepherd DM, Stamenkovic I, Ledbetter JA, Aruffo A: A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. Proc Natl Acad Sci U S A. 1992 Jul 15;89 (14) :6550-4., URL: https://www.ncbi.nlm.nih.gov/pubmed/1378631?itool=
