Anti-Hu CD229 Purified
CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.
Product Specifications
Certification
RUO
Immunogen
CD299-transfected 300.19 pre-B cell line
Target Antigen
CD229
Clone
HLy9.25
Applications
FC (QC tested), IP, WB, ICC
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Other References
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
Applications Notes
Flow cytometry: Recommended dilution: 6 μg/ml; positive control: peripheral blood lymphocytes.
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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