Anti-Hu CD162 Purified
CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.
Product Specifications
Certification
RUO
Immunogen
Human thymocytes
Target Antigen
CD162
Clone
TC2
Applications
FC (QC tested)
Concentration
1 mg/mL
Format
Purified
Buffer
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
References & Citations
Other References
Storage Conditions
Store at 2-8°C. Do not freeze.
Specificity
+
Applications Notes
Flow cytometry: Recommended dilution: 1.5 - 2.5 μg/ml; positive control: human peripheral blood.
Species
Human
CAS Number
9007-83-4
Isotype
Mouse IgG1
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